Publikationer
- Comparison of SP142 and 22C3 PD-L1 assays in a population-based cohort of triple-negative breast cancer patients in the context of their clinically established scoring algorithms
Sigurjonsdottir G, De Marchi T, Ehinger A, Hartman J, Bosch A, Staaf J, Killander F, Niméus E.
Breast Cancer Res. 2023 Oct 10;25(1):123. - Serum copper, zinc and copper/zinc ratio in relation to survival after breast cancer diagnosis: A prospective multicenter cohort study
Bengtsson Y, Demircan K, Vallon-Christersson J, Malmberg M, Saal LH, Rydén L, Borg Å, Schomburg L, Sandsveden M, Manjer J.
Redox Biol. 2023 Jul;63:102728. Epub 2023 May 16. - Molecular characteristics of breast tumors in patients screened for germline predisposition from a population-based observational study
Nacer DF, Vallon-Christersson J, Nordborg N, Ehrencrona H, Kvist A, Borg Å, Staaf J.
Genome Med. 2023 Apr 14;15(1):25. - A prospective cohort study identifying radiologic and tumor related factors of importance for breast conserving surgery after neoadjuvant chemotherapy
Gulis K, Ellbrant J, Svensjö T, Skarping I, Vallon-Christersson J, Loman N, Bendahl PO, Rydén L.
Eur J Surg Oncol. 2023 Jul;49(7):1189-1195. Epub 2023 Mar 28. - Subtype and cell type specific expression of IncRNAs provide insight into breast cancer
Bjørklund SS, Aure MR, Häkkinen J, Vallon-Christersson J, Kumar S, Evensen KB, Fleischer T, Tost J; OSBREAC; Sahlberg KK, Mathelier A, Bhanot G, Ganesan S, Tekpli X, Kristensen VN.
Commun Biol. 2022 Aug 18;5(1):834. - How Reliable Are Gene Expression-Based and Immunohistochemical Biomarkers Assessed on a Core-Needle Biopsy? A Study of Paired Core-Needle Biopsies and Surgical Specimens in Early Breast Cancer
Saghir H, Veerla S, Malmberg M, Rydén L, Ehinger A, Saal LH, Vallon-Christersson J, Borg Å, Hegardt C, Larsson C, Haidar A, Hedenfalk I, Loman N, Kimbung S.
Cancers (Basel). 2022 Aug 18;14(16):4000. - RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer.
Staaf J, Häkkinen J, Hegardt C, Saal LH, Kimbung S, Hedenfalk I, Lien T, Sørlie T, Naume B, Russnes H, Marcone R, Ayyanan A, Brisken C, Malterling RR, Asking B, Olofsson H, Lindman H, Bendahl PO, Ehinger A, Larsson C, Loman N, Rydén L, Malmberg M, Borg Å, Vallon-Christersson J.
NPJ Breast Cancer. 2022 Aug 16;8(1):94. - One-year recovery from breast cancer: Importance of tumor and treatment-related factors, resilience, and sociodemographic factors for health-related quality of life
Velickovic K, Borrebaeck C, Bendahl PO, Hegardt C, Johnsson P, Richter C, Rydén L, Hallberg I.
Front. Oncol. 2022 Aug 16, 12:891850. - Autoimmunity to selenoprotein P predicts breast cancer recurrence
Demircan K, Sun Q, Bengtsson Y, Seemann P, Vallon-Christersson J, Malmberg M, Saal LH, Rydén L, Minich WB, Borg Å, Manjer J, Schomburg L.
Redox Biol. 2022 Jul;53:102346. Epub 2022 May 25. - Clinical associations of ESR2 (estrogen receptor beta) expression across thousand of primary breast tumors.
Dalal H, Dahlgren M, Gladchuk S, Brueffer C, Gruvberger-Saal SK, Saal LH.
Sci Rep. 2022 Mar 18;12(1):4696. - Serum selenium, selenoprotein P and glutathione peroxidase 3 as predictors of mortality and recurrence following breast cancer diagnosis: A multicentre cohort study.
Demircan K, Bengtsson Y, Sun Q, Brange A, Vallon-Christersson J, Rijntjes E, Malmberg M, Saal LH, Rydén L, Borg Å, Manjer J, Schomburg L.
Redox Biol. 2021 Nov;47:102145. Epub 2021 Sep 21. - Association of mammographic features with molecular breast tumor profiles.
Sartor H, Zackrisson S, Hegardt C, Larsson C.
Cancer Treat Res Commun. 2021;28:100387. Pub 2021 May 9. - Psychological Resilience and Health-Related Quality of Life in 418 Swedish Women with Primary Breast Cancer: Results from a Prospective Longitudinal Study.
Mohlin Å, Bendahl PO, Hegardt C, Richter C, Rahm Hallberg I, Rydén L.
Cancers (Basel). 2021 May 6;13(9):2233. - Preexisting Somatic Mutations of Estrogen Receptor Alpha (ESR1) in Early-Stage Primary Breast Cancer
Dahlgren M, George AM, Brueffer C, Gladchuk S, Chen Y, Vallon-Christersson J, Hegardt C, Häkkinen J, Rydén L, Malmberg M, Larsson C, Gruvberger-Saal SK, Ehinger A, Loman N, Borg Å, Saal LH.
JNCI Cancer Spectr. 2021 Apr 22;5(2):pkab028. - Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer.
Cieśla M, Ngoc PCT, Cordero E, Martinez ÁS, Morsing M, Muthukumar S, Beneventi G, Madej M, Munita R, Jönsson T, Lövgren K, Ebbesson A, Nodin B, Hedenfalk I, Jirström K, Vallon-Christersson J, Honeth G, Staaf J, Incarnato D, Pietras K, Bosch A, Bellodi C.
Mol Cell. 2021 Apr 1;81(7):1453-1468.e12. Epub 2021 Mar 3. - Molecular analyses of triple-negative breast cancer in the young and elderly.
Aine M, Boyaci C, Hartman J, Häkkinen J, Mitra S, Campos AB, Nimeus E, Ehinger A, Vallon-Christersson J, Borg Å, Staaf J.
Breast Cancer Res. 2021 Feb 10;23(1):20. - Psychological Resilience and Health-Related Quality of Life in Swedish Women with Newly Diagnosed Breast Cancer.
Mohlin Å, Axelsson U, Bendahl PO, Borrebaeck C, Hegardt C, Johnsson P, Rahm Hallberg I, Rydén L.
Cancer Manag Res. 2020 Nov 24;12:12041-12051. - The mutational landscape of the SCAN-B real-world primary breast cancer transcriptome.
Brueffer C, Gladchuk S, Winter C, Vallon-Christersson J, Hegardt C, Häkkinen J, George AM, Chen Y, Ehinger A, Larsson C, Loman N, Malmberg M, Rydén L, Borg Å, Saal LH.
EMBO Mol Med. 2020 Oct 7;12(10):e12118. Epub 2020 Sep 14. - Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers.
Glodzik D, Bosch A, Hartman J, Aine M, Vallon-Christersson J, Reuterswärd C, Karlsson A, Mitra S, Niméus E, Holm K, Häkkinen J, Hegardt C, Saal LH, Larsson C, Malmberg M, Rydén L, Ehinger A, Loman N, Kvist A, Ehrencrona H, Nik-Zainal S, Borg Å, Staaf J.
Nat Commun. 2020 Jul 27;11(1):3747. - Prognostic implications of the expression levels of different immunoglobulin heavy chain-encoding RNAs in early breast cancer.
Larsson C, Ehinger A, Winslow S, Leandersson K, Klintman M, Dahl L, Vallon-Christersson J, Häkkinen J, Hegardt C, Manjer J, Saal L, Rydén L, Malmberg M, Borg Å, Loman N.
NPJ Breast Cancer. 2020 Jul 6;6:28. - Analysis of fusion transcripts indicates widespread deregulation of snoRNAs and their host genes in breast cancer.
Persson H, Søkilde R, Häkkinen J, Vallon-Christersson J, Mitelman F, Borg Å, Höglund M, Rovira C.
Int J Cancer. 2020 Jun 15;146(12):3343-3353. - Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study
Staaf J, Glodzik D, Bosch A, Vallon-Christersson J, Reuterswärd C, Häkkinen J, Degasperi A, Amarante TD, Saal LH, Hegardt C, Stobart H, Ehinger A, Larsson C, Rydén L, Loman N, Malmberg M, Kvist A, Ehrencrona H, Davies HR, Borg Å, Nik-Zainal S.
Nat Med. 2019 Oct;25(10):1526-1533. Epub 2019 Sep 30. - Cross comparison and prognostic assessment of breast cancer multigene signatures in a large population-based contemporary clinical series.
Vallon-Christersson J, Häkkinen J, Hegardt C, Saal LH, Larsson C, Ehinger A, Lindman H, Olofsson H, Sjöblom T, Wärnberg F, Ryden L, Loman N, Malmberg M, Borg Å, Staaf J.
Sci Rep. 2019 Aug 21;9(1):12184. - Agreement between molecular subtyping and surrogate subtype classification: a contemporary population-based study of ER-positive/HER2-negative primary breast cancer.
Lundgren C, Bendahl PO, Borg Å, Ehinger A, Hegardt C, Larsson C, Loman N, Malmberg M, Olofsson H, Saal LH, Sjöblom T, Lindman H, Klintman M, Häkkinen J, Vallon-Christersson J, Fernö M, Rydén L, Ekholm M.
Breast Cancer Res Treat. 2019 Nov;178(2):459-467. Epub 2019 Aug 20. - Prediction of lymph node metastasis in breast cancer by gene expression and clinicopathological models: Development and validation within a population based cohort.
Dihge L, Vallon-Christersson J, Hegardt C, Saal LH, Häkkinen J, Larsson C, Ehinger A, Loman N, Malmberg M, Bendahl PO, Borg A, Staaf J, Rydén L.
Clin Cancer Res. 2019 Nov 1;25(21):6368-6381. Epub 2019 Jul 24. - Detection of circulating tumor cells and circulating tumor DNA before and after mammographic breast compression in a cohort of breast cancer patients scheduled for neoadjuvant treatment.
Förnvik D, Aaltonen KE, Chen Y, George AM, Brueffer C, Rigo R, Loman N, Saal LH, Rydén L.
Breast Cancer Res Treat. 2019 Sep:177(2):447-455. Epub 2019 Jun 24. - Refinement of breast cancer molecular classification by miRNA expression profiles.
Søkilde R, Persson H, Ehinger A, Pirona AC, Fernö M, Hegardt C, Larsson C, Loman N, Malmberg M, Rydén L, Saal L, Borg Å, Vallon-Christerson J, Rovira C.
BMC Genomics. 2019 Jun 17;20(1):503. - Written pretest information and germline BRCA1/2 pathogenic variant testing in unselected breast cancer patients: predictors of testing uptake.
Nilsson MP, Nilsson ED, Silfverberg B, Borg Å, Loman N.
Genet Med. 2019 Jan;21(1):89-96. Epub 2018 Jun 6. - High patient satisfaction with a simplified BRCA1/2 testing procedure: long-term results of a prospective study.
Nilsson MP, Nilsson ED, Borg Å, Brandberg Y, Silfverberg B, Loman N.
Breast Cancer Res Treat. 2019 Jan;173(2):313-318. Epub 2018 oct 11. - A multicenter study investigating the molecular fingerprint of psychological resilience in breast cancer patients: study protocol of the SCAN-B resilience study.
Axelsson U, Rydén L, Johnsson P, Edén P, Månsson J, Hallberg IR, Borrebaeck CAK.
BMC Cancer. 2018 Aug 6;18(1):789. - Clinical Value of RNA Sequencing–Based Classifiers for Prediction of the Five Conventional Breast Cancer Biomarkers: A Report From the Population-Based Multicenter Sweden Cancerome Analysis Network—Breast Initiative.
Brueffer C, Vallon-Christersson J, Grabau D, Ehinger A, Häkkinen J, Hegardt C, Malina J, Chen Y, Bendahl PO, Manjer J, Malmberg M, Larsson C, Loman N, Rydén L, Borg Å, and Saal LH.
JCO Precis Oncol. 2018 Mar 9;2:PO.17.00135. eCollection 2018. - Minimizing inequality in access to precision medicine in breast cancer by real-time population-based molecular analysis in the SCAN-B initiative.
Rydén L, Loman N, Larsson C, Hegardt C, Vallon-Christersson J, Malmberg M, Lindman H, Ehinger A, Saal LH, Borg Å.
Br J Surg. 2018 Jan;105(2):e158-e168. - BRCAsearch: written pre-test information and BRCA1/2 germline mutation testing in unselected patients with newly diagnosed breast cancer.
Nilsson MP, Törngren T, Henriksson K, Kristoffersson U, Kvist A, Silfverberg B, Borg Å, Loman N.
Breast Cancer Res Treat. 2018 Feb;168(1):117-126. Epub 2017 Nov 21. - Frequent miRNA-convergent fusion gene events in breast cancer.
Persson H, Søkilde R, Häkkinen J, Pirona AC, Vallon-Christersson J, Kvist A, Mertens F, Borg Å, Mitelman F, Höglund M, Rovira C.
Nat Commun. 2017 Oct 5;8(1):788. - Targeted sequencing of BRCA1 and BRCA2 across a large unselected breast cancer cohort suggests that one-third of mutations are somatic.
Winter C, Nilsson MP, Olsson E, George AM, Chen Y, Kvist A, Törngren T, Vallon-Christersson J, Hegardt C, Häkkinen J, Jönsson G, Grabau D, Malmberg M, Kristoffersson U, Rehn M, Gruvberger-Saal SK, Larsson C, Borg Å, Loman N, Saal LH.
Ann Oncol. 2016 Aug;27(8):1532-8. ePub 2016 May 18. - Implementation of an Open Source Software solution for Laboratory Information Management and automated RNAseq data analysis in a large-scale Cancer Genomics initiative using BASE with extension package Reggie
Häkkinen J, Nordborg N, Månsson O, Vallon-Christersson J
bioRxiv Posted April 12, 2016. Preprint. - The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicentre infrastructure towards implementation of breast cancer genomic analyses in the clinical routine.
Saal LH, Vallon-Christersson J, Häkkinen J, Hegardt C, Grabau D, Winter C, Brueffer C, Tang MH, Reuterswärd C, Schulz R, Karlsson A, Ehinger A, Malina J, Manjer J, Malmberg M, Larsson C, Rydén L, Loman N, Borg Å.
Genome Med. 2015 Feb 2;7(1):20. - Svenskt samarbete för genomiska analyser av bröstcancervävnad. Grund för framtidens individualiserade cancerbehandling.
Niklas Loman.
Läkartidningen. 2014;111:CTEY.